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Technical papers, application notes and case studies from laboratory, chemistry, life science and quality control

Metrohm International
Analysis on site: Heavy metals
Metrohm International
Heavy metals such as arsenic and mercury find their way into the ground water in many regions of the world, either through natural processes or as the result of human activities. Limit values are exceeded many times over, particularly for arsenic in drinking water, in many areas. This calls for a...

3T analytik GmbH & CO. KG
qCell T auto - a fully automated QCM-D platform for surface interaction analysis
Dr. Adam L.J. Olsson, Dr. Paula Braun, Jin Zhang, 3T analytik GmbH & CO. KG
This study introduces the qCell T auto as a reliable and efficient tool for effortless long-time measurements that otherwise would have required the full hands-on attention of trained personnel. It carries all essential features of advanced Quartz Crystal Microbalance with Dissipation monitoring ...

Krüss GmbH
Inline process control of wettability by means of contact angle measurement on moving surfaces
Ming Jin, Dr. Thomas Willers, Krüss GmbH
Contact angle measurement has completed the step from the test laboratory into the production hall with regard to quality assurance for the cleaning and pretreatment of surfaces. This has been made possible thanks to the development of fast and mobile measuring technologies. We go even further wi...

Eppendorf Application Technologies S.A.
The Tip of the Iceberg: How Pipette Tips Influence Results - How to Save Money at the Wrong End
Muriel Art, Vincent Dufey, Eppendorf Application Technologies S.A.
Ulrike Gast, Eppendorf SE

With some manufacturers' tips it makes a difference if in serial pipetting (e.g. calibration), a new tip is used for each pipetting or if the series is pipetted using only one tip. This influence on the pipetting result is caused by variations in pipette tip quality. Eppendorf pipette tips were ...

Leica Microsystems GmbH
Why do we need a Pinhole in a Confocal Microscope?
Dr. Rolf T. Borlinghaus, Leica Microsystems GmbH
Whenever we use a confocal microscope and when we will have to discuss its parameters and features, inevitably the pinhole will be talked about and how its size effects the resulting images. This brief introductory text explains the meaning of the pinhole and is meant for readers who do not want ...

Xylem Analytics Germany GmbH & Co. KG
Reagent-free Measurement of COD, Nitrate and Nitrite via Optical Methods in the Lab and Online Directly in the Process
Dr. Ulrich Franke, Susanne Gollor, Xylem Analytics Germany GmbH & Co. KG
The chemical oxygen demand (COD), nitrate, nitrite and ammonium are among the central wastewater parameters, in order to ensure safe, optimized and smooth wastewater treatment processes. COD is a sum parameter, whose composition is very plant-specific due to the different contents of the respecti...

Process Raman spectroscopy for the monitoring of distillations
Dr. Clemens Minnich, S-PACT
Among the thermal separation processes, distillation has the longest tradition and has already been used to separate spirits (alcohols) from fermented food. Thanks to its driving force, the differences in vapour pressure of the components in question, adding thermal energy is already sufficient t...

Shimadzu Deutschland GmbH
Analysis of unstable compounds using online SFE-SFC
Dr. Isabelle Möller, Shimadzu Deutschland GmbH
Free radicals are short-lived molecular fragments of oxygen and are suspected of being responsible for aging processes but also for damage to cells or enzymes. Cells, however, have their own defense mechanisms to counter free radicals. Such antioxidants, like ascorbic acid or coenzyme Q10, react ...

PerkinElmer Inc.
Evaluating Cisplatin Uptake in Ovarian Cancer Cells by Single Cell ICP-MS
Stan Smith, Chady Stephan, PerkinElmer Inc.
Cisplatin, carboplatin, and oxaliplatin are the most widely used of platinum-based cancer chemotherapy drugs in the Western world. Cisplatin's effectiveness is due to its ability to bind to the DNA, resulting in DNA-platinum (Pt) adducts, which bend the DNA. The cells must then repair the DNA dam...

Analytik Jena GmbH
Preparing Biological Samples for Elemental Analysis by ICP-MS
Andrew Ryan, Analytik Jena GmbH
The transition from Atomic Absorption Spectroscopy (AAS) to Inductively Coupled Plasma - Mass Spectrometry (ICP-MS) has been gradual for the clinical industry over the past two decades. Both flame AAS and graphite furnace AAS techniques have served the industry well in hospitals, clinical institu...

Eppendorf Application Technologies S.A.
The Tip of the Iceberg: How Pipette Tips Influence Results - Not Every Tip Tolerates Every Treatment
Muriel Art, Vincent Dufey, Eppendorf Application Technologies S.A.
Ulrike Gast, Eppendorf SE

The pipetting accuracy of pipette tips by certain manufacturers may suffer after autoclaving. This was not the case for Eppendorf tips. We describe the measures which Eppendorf takes in order to avoid the negative influences of autoclaving. Furthermore, we describe how the interference of biologi...

Chemisches und Veterinäruntersuchungsamt (CVUA) Stuttgart
Determination of ethyl carbamate in stone fruit spirits, fruit marc spirits and other spirit drinks - A method validation study
Carmen Breitling-Utzmann, Kerstin Zietemann, Simone Goetz, Chemisches und Veterinäruntersuchungsamt (CVUA) Stuttgart
Ethyl carbamate (EC) is a toxic substance which can occur naturally in significant amounts in stone fruit spirits and other spirit drinks. Commission recommendation (EU) 2016/22 states that a target level of 1 mg L-1 EC should be achieved in stone fruit spirits and stone fruit marc spirits. In or...

Metrohm International
Glyphosate and AMPA in drinking water - Determination using ion chromatography with pulsed amperometric detection
Metrohm International
In March 2015, the International Agency for Research on Cancer (IARC) published a report which stated that glyphosate was "probably carcinogenic to humans". Ever since, the use of this chemical has been highly controversial. In some countries, including the USA, there are already limit values in ...