Find Latest News
Your search returned 21 results!
Search for "Helmholtz Centre for Infection Research" on entire page
- Comeback of the Biphenomycins
Biphenomycins, natural products derived from bacteria, show excellent antimicrobial activity, but have long remained out of reach for drug development. The main obstacle was the limited understandi...
- Starting point for the development of new active substances against the hospital germ
When the hospital germ Pseudomonas aeruginosa infects the body, it uses the sugar-binding protein LecA to attach itself to human cells, invade them, and form so-called biofilms. LecA thus plays a c... - Use of innovative RNA technology to intervene in phage reproduction
Phages are viruses that infect bacteria. Using phages therapeutically could be very useful in fighting antibiotic-resistant pathogens, but the molecular interactions between phages and host bacteri... - ERC grant for research into bacteriophages
In the fight against multiresistant bacteria, bacteriophages-the natural enemies of bacteria-are attracting increasing research interest. However, the targeted therapeutic application of these "bac... - Game-changer in the fight against multidrug-resistant pathogens
The development and spread of antibiotic resistance represents one of the greatest threats to global health. To overcome these resistances, drugs with novel mode of action are urgently needed. ... - Faster response to new virus variants
Viruses are masters at disguise. When they are pushed too far by our immune system, they send new virus variants into play that are no longer recognized by immune cells. They escape our immune syst... - Developing innovative approaches to combat new and re-emerging viruses
The COVID-19 pandemic has highlighted the immense risk potential posed by emerging and re-emerging viruses. There are neither approved vaccines nor specific therapies for many of these viruses. ... - New avenues for the treatment of multi-resistant pathogens
Antibiotics are a double-edged sword - they should be as toxic as possible to pathogenic bacteria while being harmless to the cells of the human body. An international research team led by the Helm...
- Activating the hidden pharmaceutical potential of bacteria
Microorganisms produce a wide variety of natural products that can be used as active ingredients to treat diseases such as infections or cancer. The blueprints for these molecules can be found in t... - A vast viral world in wastewater
Deep metagenomic sequencing of wastewater in Berlin over 17 months shows this technique could help forecast disease outbreaks and monitor the spread of human pathogens. It can also reveal thousands...
- Neutralising antibodies that target resistant bacteria
Antibiotic-resistant bacteria pose a major challenge to healthcare systems worldwide. Due to numerous resistance mechanisms, infections with the pathogen Pseudomonas aeruginosa are particularly fea... - Promising active ingredient to combat multi-resistant bacteria
The hospital pathogen Pseudomonas aeruginosa requires the sugar-binding proteins LecA and LecB to form biofilms as well as to attach to and penetrate host cells. These so-called lectins are therefo... - Interrogating disease progression and cell processes in vivo and non-invasively
Do we simply ingest a diagnostic probiotic based on programmed ribonucleic acids to analyze the intestinal health from individual cells in the future? Researchers at the Helmholtz Institute for RNA... - New type of CRISPR gene scissors could advance molecular biology diagnostics
It is an unexpected discovery by scientists at the Helmholtz Institute Würzburg in cooperation with Benson Hill, Inc. (Missouri) and Utah State University in the U.S.: They have found a nuclease, w...
- Optimized drug candidate against multi-resistant bacteria and parasites
The development of new active substances against pathogenic bacteria, parasites, fungi and viruses is gaining importance, as established antiinfectives are becoming increasingly ineffective due to ... - New CRISPR Element Regulates Viral Defense
Researchers from Würzburg, Freiburg and Leipzig discover a mechanism for prioritizing the immune response in bacteria. What tasks need to be done today, and which is the most urgent? People hav...
- Drug candidates against hospital germs
The increasing spread of resistant germs means that formerly highly effective antibiotics are often not successful anymore in treating infectious diseases. To counteract this development, the team ... - On the leap to new antiviral agents
The Federal Agency for Disruptive Innovation (SPRIND) has announced the participants of the first SPRIND Challenge "A Quantum Leap for New Antiviral Agents". From 45 applications from Germany and E...
- Nobel Prize in Chemistry 2020 for the development of CRISPR Cas9 technology
The Royal Swedish Academy of Sciences has awarded this year's Nobel Prize in Chemistry to Prof. Dr. Emmanuelle Charpentier, Scientific and Managing Director of the newly established Max Planck Unit...
- Plasma in a bag
Plastic bags coated by plasma at atmospheric pressure serve as a GMP laboratory for the cultivation of adherent cells. The plasma is used to modify the internal surface of the bag specifically, so ...
- Lung mucus gel scaffold prevents nanoparticles from getting through
Scientists at the Saarland University and the Helmholtz Centre for Infection Research (HZI) unraveled lung mucus's physical properties: They discovered that a rigid gel scaffold in lung mucus separ...