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- Opportunities and limitations for big data in addressing present and future pandemics
The use of data has played a central role in the COVID-19 pandemic, but it should come as no surprise that researchers are already looking at ways to improve data acquisition, management, and acces... - Artificial intelligence makes great microscopes better
To observe the swift neuronal signals in a fish brain, scientists have started to use a technique called light-field microscopy, which makes it possible to image such fast biological processes in 3... - SARS-CoV-2 curtails immune response in the gut
EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut's role in COVID-19. In an effort to determine the potential for COVID-19 to beg...
- Toxin responsible for Legionella growth identified
A team of scientists led by EMBL group leader Sagar Bhogaraju and Ivan Dikic of Goethe University, Frankfurt, discovered that the toxin SidJ in Legionella bacteria enforces a unique modification on... - Software tools for automated acquisition of electron microscopy data
There is a growing demand for high-throughput data acquisition in structural and cell biology research. Developments in microscopy hardware and computing performance have increased the speed and qu... - New 3D microscope to visualise fast biological processes
Researchers from EMBL Heidelberg have combined their expertise to develop a new type of microscope. The revolutionary new light-field microscopy system makes it possible to study fast biological pr... - Role reversal: RNA controls protein function
Ribonucleic acids (RNAs) perform many important roles within cells, mainly ensuring that proteins are made in the right quantities at the right times. Usually, the fate of an RNA is controlled by R... - Facilitating transcontinental human data exchange
Registered researchers will be able to analyse population-scale genomic and biomolecular data with the launch of the Common Infrastructure for National Cohorts in Europe, Canada and Africa (CINECA)...
- Discovering new enzymes just got easier
What if you could make plants produce biodegradable plastic? Make textiles without polluting the environment? Produce innovative new food ingredients? EMBL-EBI and Biocatalysts are working on it. B... - Time-resolved X-ray crystallography simplified
An international collaboration has developed a new method to observe the molecular foundations of biology, with the help of beamline P14 at EMBL Hamburg. The new 'hit-and-return' method simplifies ... - Understanding cell identity by creating maps of genetic networks
As part of a series marking the 10th anniversary of the European Research Council, ERC grantees Wolfgang Huber - EMBL group leader - and Oliver Stegle, group leader at EMBL and the German Cancer Re... - Ageing is visible in the way cells use glucose
Getting older means a few more wrinkles and grey hairs. Deep down, ageing also entails a functional decline of your cells and especially of stem cells. A research team from EMBL and Heidelberg Univ... - PhenoMeNal: an online portal for metabolomics
An international collaboration between EMBL's European Bioinformatics Institute (EMBL-EBI) and 13 other partners has made large-scale metabolomics analyses easier with the launch of PhenoMeNal. Thi... - Cohesin: a glue for DNA
Before cell division begins, a newly replicated chromosome consists of two identical threadlike strands that are joined together. Responsible for holding these sister chromatids together is a ring-... - The importance of curiosity-based research
In 1878, the Dutch chemist Jacobus Henricus van 't Hoff gave a lecture titled 'Imagination in Science'. In it, van 't Hoff describes his research into the biographies of more than 200 famous scient... - Understanding soil through its microbiome
Soil is full of life, essential for nutrient cycling and carbon storage. To better understand how it functions, an international research team led by EMBL and the University of Tartu (Estonia) cond... - Melting bacteria to decipher antibiotic resistance
With antibiotic resistance spreading worldwide, there is a strong need for new technologies to study bacteria. EMBL researchers have adapted an existing technique to study the melting behaviour of ... - Combining antibiotics changes their effectiveness
Depending on the bacterial species, some combinations stop antibiotics from working to their full potential whilst others begin to defeat antibiotic resistance, report EMBL researchers and collabor... - Counting and locating chromosomal proteins during cell duplication
Chromosomes are highly organised, dense arrangements of DNA, which form every time our cells duplicate themselves. Two protein complexes, Condensin I and II, are known to help organise DNA strands ... - New way to limit antibiotic resistance spreading
One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst them. In an attempt to help fight this thr...
- Reproduction of malaria parasites reveals faster and broader protein regulation than expected
A study led by researchers at the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute gives new insights into the life cycle of malaria-causing Plasmodium parasites... - Open imaging data for biology
A picture may be worth a thousand words, but only if you understand what you are looking at. The life sciences rely increasingly on 2D, 3D and 4D image data, but its staggering heterogeneity and si... - Developing a data coordination platform for the Human Cell Atlas
The Chan Zuckerberg Initiative (CZI) has announced financial support for the Human Cell Atlas, which is using sequencing technology to redefine every cell in the body. Funding and engineering suppo... - Important function of genetic sequence our ancestors assimilated from a virus
DNA from viruses that once infected our ancestors millions of years ago have remained in our genome to this day. In a study published today in eLife, EMBL scientists found that activation of one cl... - Structure of key system for TB infection revealed
The Wilmanns group at EMBL together with scientists from across Europe reveal the overall architecture of an assembly of proteins known as Type VII secretion systems found in a group of bacteria wh...