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Online Laboratory Magazine
12/06/2024

11/19/2024

Saccharin: safety threshold increased


EFSA has concluded that saccharin is safe for human consumption and increased the acceptable daily intake ( ADI ) from 5 to 9 mg/kg of body weight per day, published in a scientific opinion.

The ADI , which reflects the safe amount of a substance that can be consumed daily over a lifetime, covers saccharin and its sodium, calcium and potassium salts (E 954). The previous ADI was set in 1995 based on the increased incidence of bladder tumours observed in rat studies. However, there is now scientific agreement that these tumours are specific to male rats and not relevant to humans.

EFSA experts have reviewed all available data and concluded that saccharin does not cause DNA damage and that it is unlikely that its consumption is associated with cancer risk in humans. In addition, consumer exposure is below the newly derived ADI, meaning that there is no health risk.

What is saccharin?

Saccharin has been used to sweeten foods and drinks for over 100 years, becoming popular as a sugar replacement in the '60s and '70s. The salts of saccharin are used because they dissolve better in water. This makes it easier to add them to foods and drinks and can make them sweeter.

As for all food additives, saccharin and its salts must be labelled on products, allowing consumers to make informed choices. This re-evaluation is part of our broader work to review the safety of all food additives that were permitted for use in foods before 20 January 2009, as required by EU Regulation.

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Source: European Food Safety Authority (EFSA)