Principal Scientist ADME (m/f/d)

Your Qualifications:

• PhD (or equivalent) in biology, pharmacology, drug metabolism or pharmacokinetics or related disciplines with ideally long-term industrial experience
  
• In-depth knowledge of discovery DMPK, in vitro ADME and pharmacology-related topics, ideally combined with experience as a DMPK representative in cross-functional research project teams
  
• Collaborative, innovative, and proactive personality with outstanding team-working
  
• Excellent communication skills in English - both spoken and written

Your Tasks:

• As an experienced subject matter expert in DMPK, you provide solutions to ADME challenges within drug discovery programs.
  
• You sense project needs early on and consult research project teams on ADME-related topics helping to optimize drug properties, support candidate selection and thus contributing to improve overall probability of success of discovery research programs.
  
• As one of BI's drug discovery ADME scientists you are involved in overarching data integration as well as development and application of new data analysis methods to inform optimal design of discovery in vitro ADME assays.
  
• You work closely with BI's development in vitro ADME colleagues and act as an interface to vivo PK and clinical pharmacology colleagues with your understanding of how to translate in vitro ADME assays to preclinical PK and human in vivo relevance.
  
• You have substantial scientific impact on BI's drug discovery assets by standing on the scientific edge of external innovation and industry trends and you participate in external expert groups as part of the global ADME scientific community and expert network
  
• Furthermore, you will coach and support the development of (junior) research scientists.

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