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Scientist, Cancer Immunology (m/f/d)



  • PhD in Immunology, Biomedical Sciences, or a closely related field with 0-3 years of relevant experience
  • Strong skills in cell culture and aseptic techniques, as well as experience with the cultivation of primary human cells
  • Experience in immunological techniques such as activation of T cells, viral vector generation, T cell transduction, and electroporation
  • Experience with multicolor flow cytometry and assay development
  • Experience with primary T cell-based assays (e.g. ELISPOT, MSD, cytotoxicity)
  • Experience with in vivo mouse tumor models
  • Comfortable in a fast-paced environment and able embrace change, while working to produce key deliverables in accordance with project timelines
  • Strong verbal and written communication skills and ability to communicate results to a diverse cross-functional audience
  • Proactive, self-motivated team player with strong interpersonal skills, appropriate sense of urgency and the ability to work independently

Supporting BioNTech's R&D team in the US by:

  • Culturing of human T cells and cancer cell lines
  • Engineering of T cells using viral and non-viral methods
  • Performing functional and phenotypic characterization of engineered T cells by multicolor flow cytometry, MSD, and cytotoxicity assays
  • Designing and executing cell-based functional assays to evaluate T cell modifications and combination therapies in vitro
  • Developing in vivo models to study combination therapies with our TCR T cell therapy
  • Tracking and compiling results in an electronic notebook
  • Interacting with internal collaborators and external CROs
  • Assisting with the training of lab personnel
  • Presenting results to other scientific teams

» Job description

BioNTech US
Cambridge, Massachusetts [USA]