Analytik NEWS
Online Laboratory Magazine
12/02/2022

Scientist - Target Identification / Validation Expert Research Immuno-Oncology (m/f/d)

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Who You are:

  • PhD in Immunology or Biology or in related fields, MD-PhD in Immunology is a plus
  • Expert knowledge in Cancer Biology, Immuno-Oncology and Immunology
  • Prior working experience in a PostDoc position in the field of Immunology or Immuno-Oncology as well as first experiences in a pharmaceutical company or biotech in the field of Immuno-Oncology
  • Expertise, practical knowledge and track record (scientific publication) of bioinformatic data mining approaches for biology and disease understanding
  • Capability to generate scientific and therapeutic hypotheses and experimentally validate or de-validate them utilizing immunology / disease-related assays
  • Experience in a variety of techniques of cellular and molecular biology, flow cytometry and experience with in human multi-cellular in vitro / ex vivo and mouse in vivo models
  • Creative and flexible thinking, with excellent organizational skills including a sense of responsibility and urgency and ability to adapt to a dynamic research environment and the ability to work in teams as well as independently
  • Excellent verbal and written communication and presentation skills in English

Your Tasks an Resonsibilities:

  • Initiate and perform campaigns to identify new cancer drug target candidates and innovative therapeutic solutions in areas of high unmet need and resistance mechanisms in the Immuno-Oncology area
  • Lead target identification initiatives and provide biological guidance and deep disease-understanding with expertise in cancer and Immunology for data mining approaches utilizing scientific creativity, independent and out-of-the-box thinking
  • Utilize state-of the art data sources for target/ pathway identification as Real-Word data, literature databases and gene expression data (RNA seq, Single Cell seq, Exon seq, CITE seq, spatial transcriptomics) with the help of Bayer`s bioinformatics department
  • Design and execute pre-clinical strategies to validate the biology of novel drug targets as starting points for new drug discovery programs, as well as to serve as project lead for pre-clinical target validation projects
  • Independently establish and conduct immune cells assays, and cancer-related models in vitro/ex vivo/in vivo to validate novel target / pathways for relevance in the human disease
  • Follow continuously scientific developments in the field, interpret and effectively communicate scientific findings and project's progress in department and community meetings
  • Work and collaborate in a team with biologists, bioinformaticians and (bio)chemists across Bayer's pharmaceutical division as well as with external CRO and academic partners, with a specific focus on collaboration with Joint Immunotherapy Laboratory at the DKFZ (Heidelberg)
  • Work with genetically-modified, radioactively labelled and infectious material, as well as animal experiments and comply to legal requirements and regulations (as applicable: Gentechnik, Biostoffverordnung, Infektionsschutzgesetz, Tierversuchserlaubnis)


» Job description


Employer:
Bayer AG
Location:
13353 Berlin
Temporary:
No
Part-time:
No