Analytik NEWS
Online Laboratory Magazine
08/19/2022

Antibody Conjugation Scientist III, Technical Operations (m/f/d)

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How will you get here?

  • BS degree plus five (5), or MS/PhD plus three (3) years relevant manufacturing experience, or equivalent combination of education and experience (industrial experience preferred).

Knowledge, Skills, Abilities

  • Good knowledge of conjugation using Sulfhydryl and amine chemistry
  • Familiar with brilliant ultraviolet dyes and MTA conjugation method
  • Familiar with different purification methods (Protein A, Protein G, IgM purifications)
  • Familiar with using AKTA and HPLC for purification and conjugation production.
  • Proficiency with sterile/aseptic technique.
  • Basic knowledge of cell culture and cell chemistry
  • Broad based knowledge and experience in experimental design (DOE), and statistical quality, including experience with secondary vendor validations and scale-up projects.
  • Effective written and verbal communication skills.
  • Flexible team player capable of effectively managing multiple projects simultaneously.
  • Project management experience.
  • Effectively work cross functionally with representatives from other departments and teams.
  • Critically evaluate, revise, or create process documents; ensure that efficient, reproducible, quality manufacturing processes and documents are developed for new and existing products.
  • Strive to improve product quality through establishment of more effective or efficient manufacturing processes and quality testing.
  • Initiate and implement appropriate experiments to address manufacturing process failures.
  • Actively participate in New Product Development product and process development activities. Co-development with R&D or Manufacturing Sciences throughout process as required.
  • Organize and prioritize work to ensure on-time delivery.
  • Ability to lift up to 20 pounds.
  • Proficient in PC applications, including Microsoft Word, Excel, and Outlook.

What will you do?

  • Design and execute experimental studies based on the deliverables. Analyze and summarize the data and provide complete documentation.
  • Lead and complete improvement or root cause analysis projects with a high degree of complexity and scope.
  • Prepare and execute validation protocols.
  • Process development and engineering for productivity and scale/yield improvements.
  • Work cross-functionally to efficiently release products, resolve problems, and provide support to other departments across the organization.
  • Present experimental results at team meetings and seminars.
  • Provide detailed protocol (batch record) documentation for implementation in manufacturing
  • Drive improvement projects for safety, quality, and cost-reduction.


» Job description


Employer:
Thermo Fisher Scientific
Location:
Carlsbad, CA [Vereinigte Staaten]
Temporary:
No
Part-time:
No