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Scientist, Antibody Engineering (m/f/d)



  • MSc or PhD or equivalent in Molecular Biology, Biochemistry, Biotechnology, Biomedical Engineering, structural biology or related field is required
  • At least 4 years of relevant laboratory experience is preferred
  • In-depth understanding and experience of antibody engineering, managing incoming requests, conducting design and registering plasmids in a central database system is preferred
  • Experience in molecular biology techniques including bi-, multi-specifics, scFv, and/or chimeric antigen receptor (CAR) construct design and cloning is preferred
  • Demonstrated experience working in a cross-functional organization
  • Maintain accurate inventory of generated plasmids, lab notebooks, and other records and writing of technical reports, summaries, protocols, and manuscripts are preferred
  • Strong written and oral communication skills are required
  • Experience with protein production using transient transfection/stable cell line generation using CHO and HEK-293 is preferred
  • Proficient knowledge of cellular/molecular biology, common biology laboratory assays such as ELISA, Luminex, and biolayer interferometry (Octet) and other assays are preferred

Key Responsibilities:

  • Design and clone antibody and protein based molecular entities
  • Support the broad lead engineering efforts in the modality agnostic Therapeutics Discovery organization
  • Perform and expand established assays as well as develop and optimize new assays. Responsibilities will include cloning, plasmid scale-up, plasmid QC, cell culture, reagent preparation, E. coli and mammalian cell culture, ELISA and other binding assays and flow cytometry.
  • Be able to independently process data, interpret results, update the database, and present results to applicable functional groups.
  • Manage laboratory operations including such as reviewing of experimental protocols and equipment manuals, writing protocols, ordering of reagents and supplies, inventory management, instrument QC, scheduling of equipment maintenance, safety inspections
  • Train new hires and mentor other scientists, contractors, and co-op students

» Job description

Johnson & Johnson
Spring House, Pennsylvania [Vereinigte Staaten]