Scientist, Proteomics (m/f/d)

Requirements

• PhD degree in proteomics, biochemistry, biology, chemistry or relevant field
  
• 5+ years of relevant research experience in academia or industry
  
• Strong background in biochemistry, cell biology, molecular biology, biotechnology and immunology
  
• Familiarity with proteomic workflows for sample processing (enzymatic digestion of proteins, chemical modification of peptides such as iTRAQ/TMT, desalting, fractionation, isobaric tag labeling, etc.)
  
• Familiarity with nanoLC-MS/MS workflows for data acquisition including unbiased and targeted data collection and MS-based quantitative assays
  
• Familiarity with biochemical purification techniques, such as extraction, ultracentrifugation, and chromatography
  
• Familiarity with data processing workflows, such as database searching programs and quantitative software such as Skyline
  
• Ability to organize and tabulate data
  
• Excellent attention to detail and record-keeping skills
  
• Ability to maintain inventories of equipment, supplies, and related research materials
  
• Ability to work independently as well as part of a collaborative, matrix environment
  
• Strong written and oral communication skills
  
• Independent, flexible, self-motivated, curious, and the ability to work well with others
  
• Exposure to R or other statistical tools

Responsibilities

• Sample preparation for nanoLC-MS/MS analysis, including desalting, chemical modification, fractionation, and isobaric tag labeling
  
• Optimization and execution of immunopurification and other enrichment strategies
  
• Method development and implementation of protein purification strategies for isolation of membrane and intracellular proteins from cells and tissues
  
• Participate in cell culture and sample generation
  
• Instrument maintenance (Thermo instruments)
  
• nanoLC-MS/MS analyses of biologically derived protein and peptide mixtures
  
• Analysis of nanoLC-MS/MS data and post-processing of data
  
• Contributions to nanoLC-MS/MS experimental design
  
• Review of scientific literature and collaboration with cross-functional teams
  
• Tracking and compiling of results in an electronic notebook
  
• Assisting with training of lab personnel
  
• Presentation of results to cross-functional teams>/ul>
  
  

  » Job description

  
  
  Employer:
  BioNTech US
  Location:
  Cambridge, Massachusetts [UK]
  Temporary:
  No
  Part-time:
  No