Analytik NEWS
Online Laboratory Magazine
06/26/2022

Scientist, Proteomics (m/f/d)

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Requirements

  • PhD degree in proteomics, biochemistry, biology, chemistry or relevant field
  • 5+ years of relevant research experience in academia or industry
  • Strong background in biochemistry, cell biology, molecular biology, biotechnology and immunology
  • Familiarity with proteomic workflows for sample processing (enzymatic digestion of proteins, chemical modification of peptides such as iTRAQ/TMT, desalting, fractionation, isobaric tag labeling, etc.)
  • Familiarity with nanoLC-MS/MS workflows for data acquisition including unbiased and targeted data collection and MS-based quantitative assays
  • Familiarity with biochemical purification techniques, such as extraction, ultracentrifugation, and chromatography
  • Familiarity with data processing workflows, such as database searching programs and quantitative software such as Skyline
  • Ability to organize and tabulate data
  • Excellent attention to detail and record-keeping skills
  • Ability to maintain inventories of equipment, supplies, and related research materials
  • Ability to work independently as well as part of a collaborative, matrix environment
  • Strong written and oral communication skills
  • Independent, flexible, self-motivated, curious, and the ability to work well with others
  • Exposure to R or other statistical tools

Responsibilities

  • Sample preparation for nanoLC-MS/MS analysis, including desalting, chemical modification, fractionation, and isobaric tag labeling
  • Optimization and execution of immunopurification and other enrichment strategies
  • Method development and implementation of protein purification strategies for isolation of membrane and intracellular proteins from cells and tissues
  • Participate in cell culture and sample generation
  • Instrument maintenance (Thermo instruments)
  • nanoLC-MS/MS analyses of biologically derived protein and peptide mixtures
  • Analysis of nanoLC-MS/MS data and post-processing of data
  • Contributions to nanoLC-MS/MS experimental design
  • Review of scientific literature and collaboration with cross-functional teams
  • Tracking and compiling of results in an electronic notebook
  • Assisting with training of lab personnel
  • Presentation of results to cross-functional teams>/ul>


    » Job description


    Employer:
    BioNTech US
    Location:
    Cambridge, Massachusetts [UK]
    Temporary:
    No
    Part-time:
    No