Online Laboratory Magazine

Scientist I (m/w/d)



  • Bachelor's degree or equivalent with typically 5 years of relevant experience or MS with 2 years of experience either in academic or industry setting
  • Proven track record that demonstrates the ability to design, execute and interpret experiments
  • Hands on experience in lentiviral production and transduction, stable cell line development and CRISPS-cased gene editing
  • Proficient in nucleic acid extraction/purification, qRT-PCR, western blotting/WES, ELISA/MSD, flow cytometry, viability assays and compound screening and other cell and molecular biology techniques
  • Experience with bioinformatic analysis of multi-OMICS data is preferred
  • Excellent knowledge in cell biology models to elucidate the mechanism of action of novel oncology targets
  • Knowledge of current technological advancements/trends in areas of oncology research
  • Ability to manage more than one project at any given time and to work successfully in a cross-functional and highly collaborative team environment
  • Good communication, both speech and writing, to a variety of audiences
  • Experience with working in a fast-paced environment and ability to meet expected deadlines


  • Designing and executing experiments to inform cancer target biology using a variety of cellular/molecular and functional genomics approaches, including CRISPR-mediated cell line engineering, analysis of signaling pathway and characterization of cell death mechanism(s)
  • Utilizing knockdown, knockout, knockin and over-expression of protein for target validation
  • Identifying and validating pharmacodynamic readouts for novel oncology targets
  • Collect, analyze, and summarize data for presentations, reports, publications, and patents
  • Maintain an up-to-date understanding of new technologies and relevant scientific advances in tumor dependencies and its roles in cancer from literature and scientific meetings

» Job description

AbbVie Inc.
San Francisco [USA]