Scientist Protein Engineering (m/f/d)
- Doctoral degree in natural sciences (e.g. biology, immunology, biochemistry, pharmacy)
- Extensive experience in protein engineering field (e.g. antibody or protein scaffold discovery, expression and characterization)
- Experience with different protein expression systems, preferably E. coli as well as mammalian cells
- Affinity for technology and streamlining of workflows using liquid handling and automated magnetic bead processing
- Experience in phage display technology or similar directed evolution techniques like yeast surface display, bacterial display or mammalian display is highly desirable
- Plan and perform manual and semi-automated phage display selection campaigns for the identification of target-specific single domain antibodies
- Continuously improve the selection and hit identification process
- Formalize the improved methods as standard operation procedures (SOPs)
- Produce target-specific ligands in pro- and eukaryotic expression systems and characterize them e.g. in terms of biophysical properties and binding kinetics
- Documentation and reporting of the work in the course of department and project meetings
Employer:
BioNTech AG
Location:
55131 Mainz