Gesellschaft Deutscher Chemiker (GDCh)

Safety & Selectivity in the Scale Up of Chemical Reactions


The aim of the course is to give lab chemists an understanding of the issues that need to be considered during the early stages of scale up to large laboratory scale equipment (10-20 litre vessels) / kilo lab. The course will concentrate on chemical safety and selectivity issues and include information on what safety testing equipment is available and the uses and limitations of this equipment. Attendees will learn how to identify potential problems whether they be thermal hazards or selectivity issues. Methods used by other companies for handling hazardous reagents and reactions will be described as well as alternative chemistry to circumvent these reactions and / or reagents.

Detailed Course Contents:

  • Introduction
  • Improving safety and selectivity in chemical reactions
  • Thermal Hazard Testing and Runaway Reactions
  • Oxidation
  • Reduction
  • Solvent Selection and Solvent Effects
  • Azide and Diazo Chemistry
  • Scaling up chemical reactions
  • Work Up
  • C-C Bond Forming Reactions
  • Curtius and Related Rearrangements

Target group:

Any laboratory chemist involved in the scale-up to large scale equipment / kilo lab.

» Details

Gesellschaft Deutscher Chemiker (GDCh)
Event Type:
03/28/2019 - 03/29/2019
Frankfurt am Main

Gesellschaft Deutscher Chemiker e.V.
Postfach 90 04 40
D-60444 Frankfurt am Main

Tel.: +49 69 7917-364/-291
Fax: +49 69 7917-475
Mail: Send request Contact